Scientists warn that a common condiment could make life-saving drugs ‘less effective’

Madeline Cove
The Nightly
Cinnamon has long been popular for its supposed health benefits and is frequently used by people looking to lower blood pressure or blood sugar. 
Cinnamon has long been popular for its supposed health benefits and is frequently used by people looking to lower blood pressure or blood sugar.  Credit: Viacheslav Yakobchuk - stock.adobe.com

A new study has raised concerns about a widely used spice, suggesting it may interfere with how the body processes certain prescription medications.

Researchers found that cinnamaldehyde — the compound that gives cinnamon its signature flavour and aroma — may accelerate drug metabolism, potentially reducing the effectiveness of medications by prompting the body to clear them too quickly, The Daily Mail reports.

“Overconsumption… could lead to a rapid clearance of the prescription medicine from the body, and that could result in making the medicine less effective,” principal scientist Shabana Khan explained.

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While the everyday use of cinnamon in foods and beverages is considered safe, the study highlights a potential risk for those taking cinnamon supplements, which often contain highly concentrated levels of cinnamaldehyde.

Cinnamon has long been popular for its supposed health benefits and is frequently used by people looking to lower blood pressure or blood sugar.

Khan noted that relatively few studies have directly examined how cinnamaldehyde interacts with other substances in the body, particularly prescription drugs.

“Understanding its bio-accessibility, metabolism, and interaction with xenobiotic receptors was important to evaluate how excess intake of cinnamon would affect the prescription drugs if taken at the same time,” she said.

Cinnamon is already known to interact with at least 47 medications, including common blood thinners like aspirin and warfarin, where it can increase the risk of bleeding.

Researchers found that cinnamaldehyde may accelerate drug metabolism, reducing the effects of medicine.
Researchers found that cinnamaldehyde may accelerate drug metabolism, reducing the effects of medicine. Credit: Marcus Z-pics - stock.adobe.com

The new findings suggest the spice may have broader interactions than previously understood, though further research is needed.

The form of cinnamon also plays a role.

Cinnamon bark, commonly sold in supermarkets and used in supplements, contains high levels of both cinnamaldehyde and coumarin, a naturally occurring blood thinner. This combination could pose complications for individuals already on anticoagulant medications.

In contrast, cinnamon oil, often used in cooking and personal care products, was found to pose minimal risk.

Despite these concerns, cinnamon continues to be promoted for its potential health benefits, including antioxidant properties and its possible ability to reduce cholesterol and triglycerides.

Some, like longevity expert Dr Michael Aziz, have even suggested it may lower the risk of Alzheimer’s disease. Though these claims remain unproven and require more scientific validation.

Khan urged caution, especially among individuals managing chronic health conditions.

“People who suffer from chronic diseases such as hypertension, diabetes, cancer, arthritis, asthma, obesity, HIV, AIDS or depression should be cautious when using cinnamon or any other supplements,” she urged.

“Our best advice is to talk to a health care provider before using any supplements along with prescription medicine. By definition, supplements are not meant to treat, cure or mitigate any disease.”

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