Collingwood have tormented Brisbane yet again, inflicting the first defeat of their AFL premiership defence as Nick Daicos ran riot in a 52-point Gabba thumping.

Daicos was dominant throughout for the Magpies’ fifth-straight win with 38 disposals, eight clearances and a goal to end the Lions’ 10-match unbeaten streak in a brutal fashion 16.9 (105) to 7.11 (53).

And veteran Scott Pendlebury declared it was the beginning of a new era for his 22-year-old teammate, who is shaking tags better than ever before.

“I think Nick’s starting to really show now it doesn’t matter what you do,” Pendlebury told Channel 7.

“He got flattened in the middle .. and then next minute he’s getting the next handball out of the contest. He’s a phenomenal player and a joy to play with, he works so hard.”

Brisbane’s last loss was in Round 23 last season when Collingwood produced a one-point escape act at the MCG, the scene of their memorable 2023 grand final nail-biter.

This time the Pies dominated a spiteful clash in front of a sell-out crowd of 34,802.

Daicos, who said Collingwood sought to run as much as possible with an extra day of rest over Brisbane, reiterated he prepares for the attention most weeks.

“But I just want to play a good team game and I was able to do that tonight,” he said.

“Just bring my pressure around the ball regardless of who’s running with me, and we sort of love it.

“We think it opens up Steele (Sidebottom), Pendles, Jack Crisp, Ned Long, those players to really get involved in the game — we think we can manipulate it. It’s a big one for us.”

Although the Lions had taken their mantle as the AFL’s “comeback kings” in the past nine months, the match was as good as over when Jamie Elliott celebrated his 200th game with his second goal for a 42-point lead late in the third term.

Along with Daicos, Bobby Hill was near his freakish best and Jordan De Goey made a successful return from injury with two goals as the visitors flexed their premiership credentials.

In a match full of flashpoints, it was the Magpies who were able to keep the cool in a fast and furious first half and punish a frustrated Brisbane on their home deck.

Collingwood looked on from the start, dominating the clearances and stifling Brisbane’s ball movement.

The Daicos brothers were everywhere with 21 disposals between them in the first term alone while former Lion Daniel McStay slotted two majors for a 10-point quarter-time lead.

Brisbane wrested control back for much of an intense second term but squandered their opportunities and were made to pay.

In contrast, with Nick Daicos running amok, the visitors were clinical, converting their limited entries to stretch their lead to 19 at half-time.

McStay’s third goal, from a controversial free kick for a push on the goal line, capped an amazing passage of play where Hill raced down the Vulture St wing and regathered several times.

Mason Cox, a late inclusion with Lachlan Sullivan scratched, took out Jack Payne in the lead-up and was targeted in a vicious melee which followed.

It was the second goal to have the home fans hot under the collar after Josh Daicos previously converted the spoils from a generous 50m free — measured at 77m — from the umpires after Zac Bailey encroached in defence.

But Brisbane could complain little at the result as they were completely outplayed throughout and kept to three goals in the second half.

Magpies captain Darcy Moore finished under an injury cloud after copping a knee to the head from teammate Jeremy Howe.

The skipper said he needed stitches to repair cartilage in his ear but never reported any concussion symptoms.

- with 7NEWS