The Sydney Swans say they are “extremely shocked and disappointed” after several players were involved in an alleged incident at their Melbourne hotel, with police investigating a report of a sexual assault.

Channel 7’s Caroline Wilson revealed the five players assisting police with the investigation are Isaac Heeney, Chad Warner, Nick Blakey, Riley Bice and James Jordon.

WATCH THE VIDEO ABOVE: Five Sydney Swans players assisting police with investigation

“All spoke and were interviewed by police today and I now understand are making their way back to Sydney from Melbourne,” Wilson said on 7NEWS.

“I understand they are all driving back to Sydney and the big question is what Sydney do next.”

Wilson said the five players spoke to police voluntarily and stressed they hadn’t been arrested.

The Swans are now holding crisis talks about their next move with the potential of standing down players looming large.

“They’re definitely looking at standing the players down, quite apart from anything else that might have happened for the fact that they were out late and allegedly drinking,” Wilson said.

“Again, that’s being investigated by the club. I think the AFL view is that one game, Round 24, which isn’t going to have any real impact on the club’s fortunes, probably will not make the statement that both the club and the AFL felt should be made at the very least, if even being most generous about what happened in Melbourne on Sunday night.”

The AFL integrity unit are also investigating.

Sydney are locked in to second place on the ladder regardless of the result in Sunday’s final match of the season against North Melbourne.

The Swans will host a qualifying final in the first week of the finals, but the police investigation puts a massive cloud over the club as they hunt a premiership.

Police attended the Pullman on Monday morning, the day after Sydney’s 36-point win over Essendon at the nearby MCG.

Channel 7’s Tom Morris reported three women had confronted Swans staff in the hotel foyer at 7.30am on Monday with coach Dean Cox said to be shocked during the scene.

7NEWS chief AFL reporter Mitch Cleary revealed some of the players went out for drinks at Harlow Bar in Richmond before the party continued at the Pullman.

More details emerged later on Monday night with 7NEWS chief reporter Chris Reason saying witness said they saw a “hysterical” and “upset” woman demanding to be let up to the room.

“We’re getting reports from witnesses inside the foyer of the hotel at 7am this morning who saw two women, one of them hysterical, deeply upset, demanding to be let back upstairs to the room to retrieve their possessions,” Reason said on 7NEWS.

“One of them saying that they felt that they were touched and surrounded by multiple men.”

Sydney on Monday morning confirmed “several players were involved” in the alleged incident and said they notified the AFL and “relevant authorities”.

“We’re still piecing together exactly what’s transpired here,” Swans chief executive Matthew Pavlich said at a brief afternoon press conference.

“Safe to say we’re extremely shocked and disappointed that this has taken place and that the players have found themselves in this situation.”

Asked whether any players were arrested, he declined to provide any details.

“As I said it’s a police matter ongoing, I’m not going to comment any further right now. Appreciate your time, thank you,” Pavlich said to wrap up the one-minute conference.

Victoria Police earlier issued a statement confirming it had opened an investigation into “a report of a sexual assault”.

“The incident occurred at a hotel on Wellington Parade in the early hours of the morning,” police said.

“The exact circumstances are yet to be established and the investigation into the incident remains ongoing.”

Morris said the situation “could rock Sydney’s season”, adding the details “are believed to be sensitive and potentially very damaging to star players”.

Sydney’s win over the Bombers secured second spot on the ladder two weeks out from their first final.

It was also a rare MCG game for the Swans after playing just two games at the ground last year and only one, in Round 2, so far this season.

If you or someone you know needs help, contact 1800 RESPECT (1800 737 732), Sexual Assault Counselling Australia (1800 211 028) or Lifeline (13 11 14).